Common BrandsCompanyUnit DosePrice
L – FolinikYash800mcg Tabs30’s=KSh. 500.00
M – FolateNic15mg Tabs1 x 15’s=KSh. 345.00


15mg OD


An adjunct treatment in patients with major depressive disorders who have a partial response or no response to SSRIs.


Allergy to the drug or any excipient of the formulation.

Side Effects:

Allergic reactions (rare); insomnia; anxiety; sore muscles; aches; acne; rash; irritability; nausea; headaches; migraines.

Pregnancy Risk Category:


Issues for Consideration:

Folic acid is converted into Dihydrofolate (DHF), Tetrahydrofolate (THF), and then finally into L-methylfolate (5 – MTHF) to be used in the body.

L – methylfolate together with antidepressants is more effective in improving depressive symptoms than antidepressant monotherapy and it results in symptomatic improvement more rapidly than SSRI/SNRI monotherapy.