Genital Ulcer Syndrome (GUC)

Mainly caused by chancroid, syphilis and herpes genitalis.

Symptoms:

Genital ulcers with/without pain.

Diagnosis:

History & physical examination especially of ulcers & buboes.

***If buboes are absent and not sexually active in the last 3 months.

Diagnosis:

Herpes genitalis?

Treatment:

Tabs acyclovir 400mg TID x 1/52

Advise of HIV testing.

***If buboes are present and sexually active in the last 3 months.

Treatment:

  1. Inj Benzathine benzylpenicillin 2.4 IM 2.4 MU STAT
  2. Tabs Erythromycin 500mg TID x 1/52

***If allergic to penicillins, give only

Tabs Erythromycin 500mg TID x 14/7

***Alternative treatment B

Inj Ceftriaxone 250mg OD x 10 – 14 days.

***Other options;

  1. Inj. Benzathine benzylpenicillin 2.4 IM 2.4MU STAT
  2. Tabs acyclovir 400mg TID x 1/52 if HIV positive or the status is unknown.

***If ulcers have not improved after a week add Tabs Azithromycin 1gm STAT